Document 0525
 DOCN  M9550525
 TI    [Comparison between CSF samples from AIDS and non AIDS patients with
       neurocryptococcosis]
 DT    9505
 AU    dos Reis-Filho JB; Matas SL; Fischman O; Morales BC; Juliano Y; Setor de
       Liquido Cefalorraquiano-Escola Paulista de Medicina,; Sao Paulo/SP,
       Brasil.
 SO    Rev Inst Med Trop Sao Paulo. 1994 May-Jun;36(3):225-30. Unique
       Identifier : AIDSLINE MED/95158763
 AB    Neurocryptococcosis was a rare nervous system infection. With the rising
       number of patients with AIDS it became a very frequent disease. This
       infection is supposed to infect patients with some kind of
       immunodeficiency and the CSF alterations often simulate tuberculous
       meningitis. The purpose of this research was to compare the CSF changes
       in AIDS and non-AIDS patients with meningoencephalitis caused by Cr.
       neoformans. There were analysed 41 CSF samples from non-AIDS patients
       with neurocryptococcosis and 23 CSF samples from AIDS patients with
       neurocryptococcosis. The results of this research allowed to conclude
       that the inflammatory changes in the CSF from AIDS patients showed a
       lower intensity compared to those non-AIDS patients. These results
       showed as well, that the CSF samples from non-AIDS patients always
       revealed some changes besides the yeast cells. In some samples of AIDS
       patients, however the unique change was the presence of the yeast. It
       was demonstrated also, that the presence of Cr. neoformans in CSF, not
       accompanied by any other change, may suggest that is a patient with
       AIDS. In non-AIDS patients CSF alterations often simulates tuberculous
       meningitis. However these alterations were rare in AIDS patients. The
       yeast cells were more numerous in CSF samples from AIDS patients than in
       those from non-AIDS patients.
 DE    Acquired Immunodeficiency Syndrome/*CEREBROSPINAL FLUID  Comparative
       Study  English Abstract  Human  Meningitis, Cryptococcal/*CEREBROSPINAL
       FLUID  Meningoencephalitis/*CEREBROSPINAL FLUID/MICROBIOLOGY  Support,
       Non-U.S. Gov't  CLINICAL TRIAL  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).