Document 0031
 DOCN  M9580031
 TI    [Cerebral toxoplasmosis with central diabetes insipidus and
       panhypopituitarism in a patient with AIDS]
 DT    9506
 AU    Brandle M; Vernazza PL; Oesterle M; Galeazzi RL; Medizinische Klinik A,
       Kantonsspital St. Gallen.
 SO    Schweiz Med Wochenschr. 1995 Apr 8;125(14):684-7. Unique Identifier :
       AIDSLINE MED/95249946
 AB    Endocrine disorders in the course of HIV infection are often a result of
       opportunistic infections of endocrine organs. We describe the case of a
       30-year-old HIV positive man in whom diabetes insipidus developed
       initially with no abnormal findings in cranial magnetic resonance
       imaging. 2 months later the patient presented with symptoms of
       panhypopituitarism. At this time, neuroradiologic examination was
       consistent with cerebral toxoplasmosis. Symptoms and neuroradiologic
       findings improved after treatment for cerebral toxoplasmosis.
       Toxoplasmosis is the most frequent opportunistic infection of the brain
       in patients with AIDS. In HIV positive patients with malfunction of the
       hypothalamic-hypophyseal system cerebral toxoplasmosis must be
       considered in differential diagnosis. Treatment of this disorder may
       alleviate symptoms and signs of endocrine malfunction.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult  AIDS-Related
       Opportunistic Infections/*DIAGNOSIS  Brain/PATHOLOGY  Case Report
       Diabetes Insipidus/*COMPLICATIONS  English Abstract  Human
       Hypopituitarism/*COMPLICATIONS/DIAGNOSIS  Magnetic Resonance Imaging
       Male  Toxoplasmosis, Cerebral/COMPLICATIONS/*DIAGNOSIS  JOURNAL ARTICLE

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