Document 0166
 DOCN  M9580166
 TI    Isolation of nontuberculous, non-avium mycobacteria from patients
       infected with human immunodeficiency virus.
 DT    9506
 AU    Raszka WV Jr; Skillman LP; McEvoy PL; Robb ML; Department of Pediatrics,
       William Beaumont Army Medical Center,; El Paso, Texas 79920.
 SO    Clin Infect Dis. 1995 Jan;20(1):73-6. Unique Identifier : AIDSLINE
       MED/95244756
 AB    Mycobacterium avium serovars account for 97% of typeable M. avium
       complex (MAC) organisms causing infection in patients with AIDS. We
       reviewed 216 consecutive cultures that yielded nontuberculous
       mycobacteria (NTM) from 212 patients. Only the first isolate of each
       species of NTM recovered from each patient was analyzed in the study.
       Among the 92 patients infected with the human immunodeficiency virus, 96
       NTM organisms were identified; M. avium was recovered from 50 (77%) of
       the 65 NTM-positive cultures of blood or bone marrow, while
       Mycobacterium intracellular and other non-avium NTM accounted for 18%
       and 5% of the isolates, respectively. Little difference in the
       susceptibility of isolates to antibiotics was noted between HIV-positive
       and HIV-negative patients or between M. avium and M. intracellulare.
       These data demonstrate that HIV-positive patients develop disseminated
       disease with NTM other than M. avium more frequently than has been
       previously reported and that these patients do not appear to be infected
       with NTM that are more resistant to antimicrobial agents than are NTM
       isolated from HIV-negative patients.
 DE    Adolescence  Adult  Aged  Aged, 80 and over  AIDS-Related Opportunistic
       Infections/DRUG THERAPY/*MICROBIOLOGY  Child  Child, Preschool  Drug
       Resistance, Microbial  Female  Human  Infant  Male  Middle Age
       Mycobacterium/CLASSIFICATION/DRUG EFFECTS/ISOLATION & PURIF
       Mycobacterium avium Complex/CLASSIFICATION/DRUG EFFECTS/ISOLATION  &
       PURIF  Mycobacterium avium-intracellulare Infection/COMPLICATIONS/DRUG
       THERAPY/MICROBIOLOGY  Mycobacterium Infections/*COMPLICATIONS/DRUG
       THERAPY/  *MICROBIOLOGY  Support, U.S. Gov't, Non-P.H.S.  JOURNAL
       ARTICLE

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