Document 0202
 DOCN  M9580202
 TI    Squamous cell carcinoma of the anus in patients with AIDS.
 DT    9506
 AU    Harrison M; Tomlinson D; Stewart S; Clare Hall Laboratories, Imperial
       Cancer Research Fund, South; Mimms, Hertfordshire, UK.
 SO    Clin Oncol (R Coll Radiol). 1995;7(1):50-1. Unique Identifier : AIDSLINE
       MED/95244359
 AB    Squamous cell carcinoma of the anus accounts for 2%-3% of all
       malignancies of the lower gastrointestinal tract. There is an increased
       incidence in homosexual males who practise receptive and anal
       intercourse [1]. We report on three cases of squamous cell carcinoma of
       the anus in patients with the acquired immune deficiency syndrome
       (AIDS), all of whom were treated with conventional radiotherapy.
       Increased normal tissue damage with delayed healing was a severe problem
       in each patient. This led to prolonged delays in delivering an adequate
       dose of radiotherapy to the site of disease. Reasons for this are
       explored and suggestions made for the treatment of such patients in the
       future.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult  Anus
       Neoplasms/*COMPLICATIONS/EPIDEMIOLOGY/RADIOTHERAPY  AIDS-Related
       Opportunistic Infections/COMPLICATIONS  Carcinoma, Squamous
       Cell/*COMPLICATIONS/EPIDEMIOLOGY/RADIOTHERAPY  Case Report  Human
       Incidence  Male  Middle Age  Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).