Document 0016
 DOCN  M9590016
 TI    Cytomegalovirus colitis in AIDS: CT features.
 DT    9509
 AU    Murray JG; Evans SJ; Jeffrey PB; Halvorsen RA Jr; Radiology Department,
       San Francisco General Hospital, CA 94110,; USA.
 SO    AJR Am J Roentgenol. 1995 Jul;165(1):67-71. Unique Identifier : AIDSLINE
       MED/95305167
 AB    OBJECTIVE. The purpose of this study was to determine the CT features of
       cytomegalovirus colitis in patients with AIDS. MATERIALS AND METHODS.
       Abdominal CT scans of 24 patients with biopsy-proved cytomegalovirus
       colitis (colonoscopy, n = 14; sigmoidoscopy, n = 8; surgery, n = 2) were
       jointly reviewed by two observers. Patients were men 26-68 years old
       (mean age, 39 years; SD, 9 years) with CD4 counts of 3-129 mm3 (mean, 32
       mm3; SD, 34 mm3). The mean interval between CT and biopsy was 6 days
       (range, 0-20 days; SD, 6 days). Scans were assessed for colonic wall
       thickening (> or = 4 mm), ulceration, mural edema, pericolonic
       stranding, ascites, lymphadenopathy, and thickening of the small-bowel
       wall. Mural involvement was recorded as asymmetric or circumferential.
       Disease location was recorded as ascending colon, transverse colon,
       descending colon, rectosigmoid colon, or pancolonic. RESULTS. Colonic
       wall thickening of 8 to 33 mm (mean, 15 mm; SD, 6 mm) was seen in 22
       patients. One patient had pancolonic involvement. The ascending colon
       was involved in 13, the transverse colon in five, the descending colon
       in 10, and the rectosigmoid colon in 16. Circumferential colonic
       thickening was seen in 17 patients. Deep mural ulceration was seen in 15
       patients, mural edema in 15, pericolonic stranding in 23, ascites in 10,
       lymphadenopathy in four, and small-bowel involvement in 10. Two patients
       had appendicitis. Three patients had perforations (two rectal, one
       cecal). One patient had a giant rectal ulcer. CONCLUSION. Although many
       of the CT features of cytomegalovirus colitis are nonspecific, the
       diagnosis should be suggested when CT shows colonic wall thickening,
       particularly if the thickening is associated with mural ulceration in
       patients with AIDS and CD4 counts of less than 200 mm3.
 DE    Adult  Aged  AIDS-Related Opportunistic Infections/*RADIOGRAPHY
       Colitis/*RADIOGRAPHY  Colon/RADIOGRAPHY  Cytomegalovirus
       Infections/*RADIOGRAPHY  CD4 Lymphocyte Count  Human  Male  Middle Age
       *Tomography, X-Ray Computed  JOURNAL ARTICLE

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