Document 0156
 DOCN  M9590156
 TI    HIV-1 variants in South and South-East Asia.
 DT    9509
 AU    Tsuchie H; Saraswathy TS; Sinniah M; Vijayamalar B; Maniar JK; Monzon
       OT; Santana RT; Paladin FJ; Wasi C; Thongcharoen P; et al; Research
       Institute for Microbial Diseases, Osaka University,; Japan.
 SO    Int J STD AIDS. 1995 Mar-Apr;6(2):117-20. Unique Identifier : AIDSLINE
       MED/95298893
 AB    HIV spread in South and South-East Asia is most alarming, and genetic
       variability of HIV-1 is an important consideration in vaccine
       development. In this study, we examined the third variable (V3) region
       of env gene of HIV-1 variants prevalent in Thailand, Malaysia, India,
       and the Philippines. By phylogenetic tree analyses, an HIV-1 variant
       from an injecting drug user (IDU) in Thailand belonged to subtype B, and
       HIV-1 variants from 2 IDUs in Malaysia were classified into 2 subtypes,
       B and E. One HIV-1 variant from a male homosexual in the Philippines
       belonged to subtype B. Out of 8 HIV-1 variants from sexually transmitted
       disease patients in India, 7 belonged to subtype C, and one to subtype
       A. Although the total number of individuals examined in this study was
       limited, 4 HIV-1 subtypes were found in South and South-East Asia and
       large international movements of HIV-1-infected individuals in this
       region could induce global dissemination of these HIV-1 variants.
 DE    Amino Acid Sequence  Female  Genes, Viral/GENETICS  Homosexuality, Male
       Human  HIV Infections/EPIDEMIOLOGY/*VIROLOGY
       HIV-1/CLASSIFICATION/*GENETICS  India/EPIDEMIOLOGY
       Malaysia/EPIDEMIOLOGY  Male  Molecular Sequence Data
       Philippines/EPIDEMIOLOGY  Phylogeny  Prostitution  Sequence Homology,
       Nucleic Acid  Support, Non-U.S. Gov't  Thailand/EPIDEMIOLOGY  *Variation
       (Genetics)  JOURNAL ARTICLE

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