Document 0248
 DOCN  M9590248
 TI    Nonconvulsive generalised epilepsy and AIDS. A case report.
 DT    9509
 AU    Hale GE; Spelman D; Alfred Hospital, Melbourne.
 SO    Annu Conf Australas Soc HIV Med. 1994 Nov 3-6;6:276 (unnumbered poster).
       Unique Identifier : AIDSLINE ASHM6/95291851
 AB    A 40 year old HIV infected patient presented with hypomania. The patient
       was diagnosed HIV positive in 1989 and suffered his first AIDS defining
       illness in 1992 (oesophageal candidiasis). At the time of presentation,
       his CD4 count was 70. His medications included zidovudine and
       cotrimoxazole. He had been functioning at a very high level as a Health
       Educator at the time of presentation. Symptoms included unusual
       behaviour, unusual perception, extreme restlessness, diminished
       concentration and feelings of being disconnected. Among other tests, an
       electroencephalogram was performed and revealed generalised epileptiform
       activity. The patient was commenced on phenytoin with immediate relief
       of the symptoms and within 2 weeks was back to full time work. The
       diagnosis of Nonconvulsive generalised status epilepticus (NCGSE) was
       made. This case demonstrates a very treatable behavioural disturbance in
       an HIV infected patient. Varied behavioural disturbances have been
       described in HIV patients, many of which are thought to be secondary to
       HIV encephalopathy or the AIDS dementia complex. In 2 large studies of
       HIV and epilepsy, the incidence of NCGSE was 4.3% and 1% respectively
       and the increased incidence of seizures in general has been described in
       several studies. This particular case cautions us against attributing
       the changes in mental status associated with NCGSE to progression of HIV
       encephalopathy and the AIDS dementia complex.
 DE    Adult  AIDS Dementia Complex/COMPLICATIONS/*DIAGNOSIS  Case Report
       Diagnosis, Differential  Electroencephalography  Epilepsy,
       Generalized/*DIAGNOSIS/ETIOLOGY  Human  Male  Organic Mental
       Disorders/DIAGNOSIS/ETIOLOGY  Status Epilepticus/*DIAGNOSIS/ETIOLOGY
       MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).