Document 0253
 DOCN  M9590253
 TI    Spinal cord disease in AIDS patients in Melbourne.
 DT    9509
 AU    Pickles R; Fuller A; Spelman D; Department of Microbiology & Infectious
       Diseases, Alfred; Hospital, Prahran.
 SO    Annu Conf Australas Soc HIV Med. 1994 Nov 3-6;6:270 (unnumbered poster).
       Unique Identifier : AIDSLINE ASHM6/95291846
 AB    AIM: To describe the clinical details of six patients with lumbosacral
       polyradiculopathy in the setting of HIV-1 infection. CLINICAL FEATURES:
       Five patients had cytomegalovirus (CMV) polyradiculopathy diagnosed on
       the basis of clinical features plus polymorphonuclear pleocytosis of
       cerebrospinal fluid, positive viral culture and/or positive polymerase
       chain reaction. The sixth patient had cryptococcal polyradiculopathy,
       diagnosed by positive culture and exclusion of other processes.
       INTERVENTION AND OUTCOME: All patients responded to specific therapy.
       Two patients with CMV later relapsed while on maintenance ganciclovir.
       The patient with cryptococcal disease relapsed on fluconazole.
       CONCLUSIONS: Lumbosacral polyradiculopathy occurs relatively frequently
       in patients with HIV-1 infection, and although many are secondary to CMV
       infection, recognition of other causes is important as they are
       potentially treatable.
 DE    AIDS-Related Opportunistic Infections/*DIAGNOSIS/DRUG THERAPY
       Cryptococcosis/*DIAGNOSIS/DRUG THERAPY  Cytomegalovirus
       Infections/*DIAGNOSIS/DRUG THERAPY  Fluconazole/ADMINISTRATION & DOSAGE
       Ganciclovir/ADMINISTRATION & DOSAGE  Human  *HIV-1
       Polyradiculitis/*DIAGNOSIS/DRUG THERAPY  Recurrence  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).