Document 0255
 DOCN  M9590255
 TI    Pseudodeafness caused by speech latency delay in patients with the HIV
       associated dementia complex.
 DT    9509
 AU    Currie J; Malone V; Maruff P; Wright E; Hoy J; Brew B; Fairfield
       Infectious Diseases Hospital, Mental Health Research; Institute of
       Victoria.
 SO    Annu Conf Australas Soc HIV Med. 1994 Nov 3-6;6:268 (unnumbered poster).
       Unique Identifier : AIDSLINE ASHM6/95291844
 AB    OBJECTIVE: To examine the nature of a novel clinical syndrome of HIV
       related pseudodeafness, caused by delayed speech initiation (DSI) in
       patients with HIV associated dementia complex (HDC). METHODS: In a
       number of HIV+ patients referred for assessment of deafness, the actual
       deficit was found to be DSI caused by HDC in the presence of normal
       hearing. We therefore devised a novel Clinical Speech Production Test
       and validated its speech initiation latencies (SILs) using computer
       analysis of digital sound recordings. RESULTS: In the 15 HDC subjects,
       SILs were significantly greater than those of HIV negative controls, or
       of subjects with cortical dementia (Alzheimer's disease) matched for
       severity of cognitive impairment. CONCLUSION: Delayed initiation of
       speech in HDC may masquerade clinically as deafness and reflects
       subcortical dysfunction.
 DE    AIDS Dementia Complex/DIAGNOSIS/*PHYSIOPATHOLOGY
       Deafness/DIAGNOSIS/*PHYSIOPATHOLOGY  Diagnosis, Differential  Human
       Reaction Time/*PHYSIOLOGY  Speech Disorders/DIAGNOSIS/*PHYSIOPATHOLOGY
       Speech Production Measurement  Verbal Behavior/PHYSIOLOGY  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).