Document 0263
 DOCN  M9590263
 TI    Incidence and implications of oral hairy leukoplakia (OHL) and
       candidiasis in a cohort of people infected with human immunodeficiency
       virus (HIV) in South Australia.
 DT    9509
 AU    Coates E; Slade G; Goss AN; Gorkic E; South Australian Dental Service,
       Adelaide.
 SO    Annu Conf Australas Soc HIV Med. 1994 Nov 3-6;6:260 (unnumbered poster).
       Unique Identifier : AIDSLINE ASHM6/95291836
 AB    OBJECTIVES: To ascertain the incidence of oral candidiasis and OHL in a
       cohort of HIV seropositive individuals in South Australia and determine
       possible significance in relation to HIV disease progression.
       METHODOLOGY: Data was collected from patients receiving care at the
       Adelaide Dental Hospital's clinic for the treatment of persons with HIV
       infection. Information was obtained from all attending patients between
       October 1992 and July 1993. Oral examination findings were recorded at
       the initial visit and at recall appointments. HIV oral conditions were
       classified according to EEC-WHO criteria. RESULTS: Fifty four patients
       were examined at the HIV dental clinic. All of them were dentate. Of
       these 32% patients had oral candida and 24.1% had OHL. CD4 counts ranged
       from less than 50 to over 1000. 6 seroconverted for HIV less than 3
       years befor examination, 17 less than 6 years and 31 between 6-10 years
       or had an unknown time of seroconversion. CONCLUSION: The conditions of
       oral candidiasis and OHL are prevalent amongst people infected with HIV
       in this country. The conditions appear before AIDS defining conditions
       and may be found at relatively high CD4 counts. Longitudinal studies
       need to be done to correlate the presence of OHL or candidiasis with any
       disease progression as Hairy leukoplakia may not have the same
       prognostic significance as in overseas countries. The prevalence of
       these manifestations could make them useful as clinical markers and also
       dictates the necessity for clinicians in the field of HIV medicine to be
       skilled oral diagnosticians.
 DE    AIDS-Related Opportunistic Infections/*EPIDEMIOLOGY/IMMUNOLOGY
       Candidiasis, Oral/*EPIDEMIOLOGY/IMMUNOLOGY  Cohort Studies
       Cross-Sectional Studies  CD4 Lymphocyte Count  Human  HIV
       Infections/*EPIDEMIOLOGY/IMMUNOLOGY  Incidence  Leukoplakia,
       Hairy/*EPIDEMIOLOGY/IMMUNOLOGY  South Australia/EPIDEMIOLOGY  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).