Document 0304
 DOCN  M9590304
 TI    Clinical challenges for positive women. National Working Group on HIV
       Infection in Women.
 DT    9509
 AU    Furner V; Thackway SV; Kaldor J; National Centre in HIV Epidemiology and
       Clinical Research,; Darlinghurst.
 SO    Annu Conf Australas Soc HIV Med. 1994 Nov 3-6;6:201 (unnumbered
       abstract). Unique Identifier : AIDSLINE ASHM6/95291795
 AB    OBJECTIVES: To provide a better understanding of the natural history of
       HIV disease in women in Australia, especially clinical manifestations
       and gynaecological conditions. METHODOLOGY: Medical records of HIV
       positive women attending participating centres were reviewed. INTERIM
       RESULTS: 204 medical records from three states were reviewed. Since
       diagnosis of HIV infection, at least 88 (43%) women have been diagnosed
       with genito-urinary conditions. Herpes simplex virus type II was the
       most common (33 cases, 16%) followed by human papillomavirus (29 cases,
       14%) and cervical dysplasia (28 cases, 14%). Since HIV diagnosis, 114
       women (56%) are reported to have undergone at least one pap smear or
       gynaecological examination. Only 46 women are reported to have undergone
       more than two gynaecological examinations. Fifty four percent of women
       had symptomatic conditions after HIV diagnosis most commonly, oral
       candidiasis (61 cases) followed by constitutional symptoms (45 cases)
       and herpes zoster (31 cases). Eighty women have received PCP
       prophylaxis. Of these, 27 (34%) have not been diagnosed with AIDS, to 30
       June 1994. Of the women who have developed AIDS, 22 received PCP
       prophylaxis previous to their AIDS diagnosis, six of these developed PCP
       as their initial AIDS defining illness. CONCLUSION: A preliminary
       analysis of this retrospective study indicates a high rate of
       genito-urinary conditions in women with HIV infection. It is probable
       that gynaecological examinations are not being carried out as widely as
       would be appropriate in this group. With 27% of women who commenced PCP
       prophylaxis prior to AIDS subsequently developing PCP raises significant
       issues in regards to compliance within this group.
 DE    Acquired Immunodeficiency Syndrome/*DIAGNOSIS/PREVENTION &  CONTROL
       Australia  AIDS-Related Opportunistic Infections/*DIAGNOSIS/PREVENTION &
       CONTROL  Female  Genital Diseases, Female/*DIAGNOSIS/PREVENTION &
       CONTROL  Human  HIV Seropositivity/*DIAGNOSIS  Multiphasic Screening
       Retrospective Studies  Risk Factors  Vaginal Smears  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).