Document 0329
 DOCN  M9590329
 TI    Pathology of the heart in the acquired immunodeficiency syndrome.
 DT    9509
 AU    Lawrence CH; Duflou J; Mathijs JM; Sears A; NSW Institute of Forensic
       Medicine, Glebe.
 SO    Annu Conf Australas Soc HIV Med. 1994 Nov 3-6;6:170 (unnumbered
       abstract). Unique Identifier : AIDSLINE ASHM6/95291770
 AB    The acquired immunodeficiency syndrome (AIDS) may involve the heart in a
       number of ways, including primary HIV myocarditis/cardiomyopathy,
       opportunistic infections of the myocardium and valves, neoplasms
       involving the heart, and cardiac failure associated with the nutritional
       and wasting conditions linked to AIDS. In the presence of a multitude of
       opportunistic infections and tumours, significant cardiac disease is
       often overlooked. We review the cardiac pathology of 48 cases autopsied
       at the NSW Institute of Forensic Medicine. The most common opportunistic
       infections detected in the heart were toxoplasmosis and cardiac
       involvement by gram negative septicaemia. Although HIV genome was
       detected using in situ hybridisation in cardiac myocytes in the majority
       of cases, we were unable to associate this finding with changes expected
       in myocarditis and cardiomyopathy.
 DE    Acquired Immunodeficiency Syndrome/*PATHOLOGY  AIDS-Related
       Opportunistic Infections/*PATHOLOGY  Heart Diseases/*PATHOLOGY  Heart
       Neoplasms/*PATHOLOGY  Heart Valves/PATHOLOGY  Human
       Myocardium/PATHOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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