Document 0330
 DOCN  M9590330
 TI    H.I.V. autopsy pathology--an update.
 DT    9509
 AU    Duflou J; Hilton JM; NSW Institute of Forensic Medicine, Glebe.
 SO    Annu Conf Australas Soc HIV Med. 1994 Nov 3-6;6:169 (unnumbered
       abstract). Unique Identifier : AIDSLINE ASHM6/95291769
 AB    Both coronial and non-coronial HIV positive autopsies have been
       performed at the NSW Institute of Forensic Medicine since early 1992. In
       1993, we presented our findings of the first 35 autopsies. In a
       comparison with antemortem diagnoses, we noted clinically significant
       discrepancies in almost half of the cases studied, well in excess of the
       expected discrepancy rate of 10 to 20%. The diseases posing the most
       diagnostic difficulty antemortem were disseminated cytomegalovirus
       infection, lymphoma and atypical mycobacterial infection. Presentation
       of our findings correlating antemortem and post mortem diagnoses has
       resulted in a greater awareness of the commonly missed diagnoses by
       clinicians, and the resultant higher index of suspicion has in part led
       to enhanced detection and treatment of these difficult to diagnose
       diseases. We now present the pathological findings in the 103 cases
       autopsied at the Institute to mid-1994. Clinico-pathological correlation
       has improved and the extent of disseminated opportunistic pathology,
       including cytomegaloviral infection and Kaposi's sarcoma has decreased
       since our previous presentation. We conclude that autopsies on HIV
       positive patients are essential in improving the management of this
       disease complex.
 DE    Autopsy  AIDS-Related Opportunistic Infections/DIAGNOSIS/*PATHOLOGY
       Cytomegalovirus Infections/DIAGNOSIS/PATHOLOGY  Diagnosis, Differential
       Human  HIV Infections/DIAGNOSIS/*PATHOLOGY  Lymphoma,
       AIDS-Related/DIAGNOSIS/*PATHOLOGY  Mycobacterium Infections,
       Atypical/DIAGNOSIS/PATHOLOGY  New South Wales  MEETING ABSTRACT

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