Document 0427
 DOCN  M9590427
 TI    Evaluation of performance of reused HIVCHEK 1 + 2 test blocks which have
       shown negative result: a reliable method for rural hospital?
 DT    9509
 AU    Acaye GL; Ansaloni L; Tocalli E; Dr Ambrosoli Memorial Hospital,
       Kalongo, Kitgum District, Uganda.
 SO    Trop Doct. 1995 Apr;25(2):54-5. Unique Identifier : AIDSLINE
       MED/95297055
 AB    The performance of the reusing of test membranes which have been used
       previously for negative tests for the detection of antibody to HIV
       (HIVCHEK 1 + 2 of Ortho Diagnostic Systems, Paris, France) was evaluated
       under field conditions. The sensitivity and specificity of the reusing
       strategy compared with a HIV determination obtained by using new
       HIVCHECK 1 + 2 tests were 89.1% and 100%, respectively. The positive
       predictive value was 100% and the negative predictive value was 91.5%.
       The authors conclude that the reduction in sensitivity of the reusing
       strategy in comparison with the use of new tests makes this strategy
       ethically unacceptable for the detection of HIV infection in blood
       donors. On the other hand, the reusing strategy could be very useful for
       diagnostic purpose and for epidemiological HIV surveillance in
       resource-poor countries.
 DE    Adult  AIDS Serodiagnosis/*INSTRUMENTATION  Collodion  *Developing
       Countries  Equipment Reuse  Female  Hospitals, Rural  Human  HIV
       Antibodies/*ANALYSIS  *HIV Seronegativity/IMMUNOLOGY  HIV-1/*IMMUNOLOGY
       HIV-2/*IMMUNOLOGY  Male  Membranes, Artificial  Predictive Value of
       Tests  Pregnancy  Uganda  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).