Document 0430
 DOCN  M9590430
 TI    Ethiopian visceral leishmaniasis patients co-infected with human
       immunodeficiency virus.
 DT    9509
 AU    Berhe N; Hailu A; Wolday D; Negesse Y; Cenini P; Frommel D; Institute of
       Pathobiology, Addis Ababa University, Ethiopia.
 SO    Trans R Soc Trop Med Hyg. 1995 Mar-Apr;89(2):205-7. Unique Identifier :
       AIDSLINE MED/95297002
 AB    This communication reports 7 Ethiopian visceral leishmaniasis (VL)
       patients co-infected with human immunodeficiency virus (HIV). The
       clinical and laboratory findings in 6 patients did not differ from
       classical VL. All patients had highly elevated anti-leishmanial antibody
       titres, determined by immunoglobulin G-based enzyme-linked immunosorbent
       assay; they most probably acquired the Leishmania infection before HIV.
       Amastigotes were identified in the splenic aspirates of 6 patients and
       in the lymph node aspirate of the 2 patients whose lymph nodes were
       examined. The CD4:CD8 lymphocyte ratio was depressed in those patients
       whose ratio was determined. Most patients showed some initial response
       to pentavalent antimonial therapy.
 DE    Adult  Animal  Antibodies, Protozoan/ANALYSIS  CD4-CD8 Ratio  Ethiopia
       Human  HIV Infections/*COMPLICATIONS  Leishmania/ISOLATION & PURIF
       Leishmaniasis, Visceral/*COMPLICATIONS/IMMUNOLOGY  Lymph
       Nodes/PARASITOLOGY  Male  Spleen/PARASITOLOGY  Support, Non-U.S. Gov't
       JOURNAL ARTICLE

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