Document 0437
 DOCN  M9590437
 TI    Disseminated histoplasmosis in a patient from a nonendemic area who has
       acquired immunodeficiency syndrome.
 DT    9509
 AU    Munis A; Habte-Gabr E; Department of Internal Medicine, Hurley Medical
       Center/Michigan; State University, Flint 48503, USA.
 SO    South Med J. 1995 Jun;88(6):651-3. Unique Identifier : AIDSLINE
       MED/95296719
 AB    Disseminated histoplasmosis is a serious opportunistic infection in
       patients with the acquired immunodeficiency syndrome (AIDS), often seen
       as the first manifestation of the syndrome. However, cases are reported
       almost exclusively from patients who live in or have traveled to endemic
       areas. We describe a case of disseminated histoplasmosis in a black
       woman with a 50-lb weight loss and marked weakness that occurred over a
       6-month period. This case is one of the few in which disseminated
       histoplasmosis occurred as the first manifestation of AIDS in a patient
       in a nonendemic area. We believe it to be the first case reported in
       Michigan in which the patient has no history of prior residence in an
       endemic area. Disseminated histoplasmosis should be suspected in
       patients with AIDS and unexplained febrile illness, even in nonendemic
       areas.
 DE    AIDS-Related Opportunistic Infections/*PATHOLOGY  Bone Marrow
       Diseases/MICROBIOLOGY/PATHOLOGY  Case Report  Fatal Outcome  Female
       Fungemia/MICROBIOLOGY/PATHOLOGY  Histoplasmosis/*PATHOLOGY  Human
       Michigan  Middle Age  JOURNAL ARTICLE

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