Document 0507 DOCN M9590507 TI Headache and the human immunodeficiency virus type 1 infection. DT 9509 AU Holloway RG; Kieburtz KD; University of Rochester (NY) School of Medicine and Dentistry,; USA. SO Headache. 1995 May;35(5):245-55. Unique Identifier : AIDSLINE MED/95293668 AB This review focuses on the prevalence, causes, evaluation, and treatment of headache in individuals infected with human immunodeficiency virus type 1 (HIV-1). Headaches, one of the commonest medical complaints in the general population, occur frequently in patients infected with the HIV-1. HIV-related headaches can occur at any time during the infection: at seroconversion, during the incubation period, in patients with symptomatic HIV-1 infection, or after an AIDS-defining illness. Causes of HIV-related headaches include HIV-1 itself, opportunistic conditions, or HIV-specific medications. Migraines, tension-type headaches, depression, and substance abuse enter into the differential diagnosis, particularly in the early stages of disease. The headaches seen in this population reflect a complex web of interactions imposed by immune competency, multiple etiologies, treatments, and premorbid conditions. Prompt recognition and early treatment of headache is essential since it may improve quality of life and, depending on the diagnosis, prolong survival. Physicians need to be alert and adaptable when assessing HIV-infected individuals with headache since multiple causes can exist in the same patient and new syndromes, complications, and investigational drugs are continually being identified. DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS/DRUG THERAPY Diagnosis, Differential Drug Interactions Headache/*COMPLICATIONS/DIAGNOSIS/DRUG THERAPY Human *HIV-1 Prognosis JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).