Document 0551
 DOCN  M9590551
 TI    The synthesis of novel HIV-protease inhibitors.
 DT    9509
 AU    Girijavallabhan VM; Bennett F; Patel NM; Ganguly AK; Dasmahapatra B;
       Butkiewicz N; Hart A; Schering-Plough Research Institute, Kenilworth, NJ
       07033, USA.
 SO    Bioorg Med Chem. 1994 Oct;2(10):1075-83. Unique Identifier : AIDSLINE
       MED/95291689
 AB    The syntheses, enzyme inhibition and antiviral activity of potent
       HIV-protease inhibitors containing novel beta-hydroxy ether and
       thioethers based on the transition state mimetic concept are discussed.
 DE    Amino Acid Sequence  Cell Line  Cytopathogenic Effect, Viral/DRUG
       EFFECTS  Ethers/CHEMISTRY/CHEMICAL SYNTHESIS/PHARMACOLOGY  HIV/DRUG
       EFFECTS  HIV Protease Inhibitors/*CHEMICAL SYNTHESIS  HIV-1/DRUG EFFECTS
       Molecular Sequence Data  Molecular Structure
       Sulfides/CHEMISTRY/CHEMICAL SYNTHESIS/PHARMACOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).