Document 0569 DOCN M9590569 TI Prevalence of human T-cell leukemia virus type 1 (HTLV-I) in adult T-cell leukemia (ATL) in non-ATL-endemic Hokkaido of Japan. DT 9509 AU Iwanaga M; Takada K; Fujiwara S; Oikawa O; Sugiura M; Imai S; Osato T; Mikuni C; Maekawa I; Miyazaki T; et al; Department of Virology, Hokkaido University School of Medicine,; Sapporo, Japan. SO In Vivo. 1994 Nov-Dec;8(6):1007-10. Unique Identifier : AIDSLINE MED/95290633 AB Sera and peripheral blood lymphocytes of 40 adult T-cell leukemia (ATL) patients in non-ATL-endemic Hokkaido were examined for the prevalence of human T-cell leukemia virus type 1 (HTLV-I). All patients had HTLV-I-specific antibodies. When the peripheral lymphocytes were assessed after short-term cultivation, HTLV-I antigens and virus particles were detected. The seroprevalence in 96 cases of non-T-cell leukemias and lymphomas and in 30,056 healthy individuals in Hokkaido were 3.1% and 0.7%, respectively. HTLV-I seropositive inhabitants of Hokkaido can be estimated at about 40,000, and one out of every few thousand HTLV-I carriers is likely to develop ATL. DE Human HTLV-I/IMMUNOLOGY/*ISOLATION & PURIF HTLV-I Antibodies/ANALYSIS HTLV-I Infections/EPIDEMIOLOGY/IMMUNOLOGY/*VIROLOGY Japan/EPIDEMIOLOGY Leukemia, Null-Cell/IMMUNOLOGY/VIROLOGY Leukemia, T-Cell/EPIDEMIOLOGY/IMMUNOLOGY/*VIROLOGY Prevalence Support, Non-U.S. Gov't JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).