Document 0584 DOCN M9590584 TI Molecular immunobiology of macrophages: recent progress. DT 9509 AU Gordon S; Clarke S; Greaves D; Doyle A; Sir William Dunn School of Pathology, University of Oxford, UK. SO Curr Opin Immunol. 1995 Feb;7(1):24-33. Unique Identifier : AIDSLINE MED/95290119 AB Macrophage molecules involved in adhesion, signalling, secretion and interactions with pathogens and T-helper lymphocytes have been cloned and defined using monoclonal antibodies and genetic disruption. Studies of the regulation of macrophage differentiation and activation by cytokines have yielded insights into the heterogeneity of their functions in natural and acquired immunity, including immunity to infections by mycobacteria and HIV. DE Animal Human Macrophages/*CHEMISTRY/*IMMUNOLOGY Molecular Biology/TRENDS Receptors, Cell Surface/*GENETICS JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).