Document 0720
 DOCN  M9590720
 TI    Pulmonary host defenses.
 DT    9509
 AU    Reynolds HY; Department of Medicine, Milton S. Hershey Medical Center,;
       Pennsylvania State University, Hershey 17033, USA.
 SO    Alcohol Clin Exp Res. 1995 Feb;19(1):6-10. Unique Identifier : AIDSLINE
       MED/95289601
 AB    Well functioning host defenses in the respiratory tract effectively
       remove microbes and other debris that reach the conducting airways and
       alveoli, and this usually prevents infections. People with acute and
       chronic illnesses can experience failure of any number of these defense
       mechanisms that allow pneumonia (and bacteremia) to occur, often with
       considerable morbidity and mortality. People with alcohol-related
       illnesses are a susceptible group for infections, and many strategies
       are needed to help them such as moderating alcohol abuse and dependence,
       providing timely immunizations to create antibody against encapsulated
       bacteria, anticipating microbial colonization of mucosal areas that can
       promote infection, giving excellent supporting medical care in crisis
       situations, and prescribing appropriate antibiotics. New approaches to
       boosting inflammatory reactions to control lung infections better with
       cytokines and new immunomodulator therapies must be investigated now.
 DE    Alcoholism/*IMMUNOLOGY  AIDS-Related Opportunistic
       Infections/*IMMUNOLOGY  Bronchi/IMMUNOLOGY  Human  Immunity,
       Cellular/IMMUNOLOGY  Immunocompetence/IMMUNOLOGY  Lung/IMMUNOLOGY
       Mucociliary Clearance/PHYSIOLOGY  Pneumonia, Bacterial/*IMMUNOLOGY
       Tuberculosis, Pulmonary/*IMMUNOLOGY  JOURNAL ARTICLE  REVIEW  REVIEW,
       TUTORIAL

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