Document 0736
 DOCN  M9590736
 TI    [Cyst-forming Coccidia: Toxoplasma, Neospora, Sarcocystis]
 DT    9509
 AU    Gottstein B; Institut fur Parasitologie, Medizinischen Fakultat,;
       Universitat Bern.
 SO    Schweiz Med Wochenschr. 1995 May 6;125(18):890-8. Unique Identifier :
       AIDSLINE MED/95288612
 AB    The most important cyst-forming coccidian parasites in human and
       veterinary medicine belong the genera of Toxoplasma, Neospora and
       Sarcocystis. Toxoplasma gondii shows its clinical relevance in
       congenital infections and opportunistic infections in immunodeficient
       patients. In veterinary medicine the parasite is predominantly the cause
       of important economic loss in livestock production. Neospora causes
       diseases resembling toxoplasmosis; neosporosis is one of the most
       important causes of bovine abortion in the US. Neospora caninum leads to
       myositis and paralysis in dogs. The potential implication of Neospora in
       toxoplasmosis-like diseases in humans is not yet known. Sarcocystis is
       usually a relatively harmless intestinal parasite in humans. Recent data
       from tropical areas suggest that man can also become an intermediate
       host for certain Sarcocystis species, which potentially represents a
       source of opportunistic infection and disease in areas with increasing
       HIV prevalence. In veterinary medicine, Sarcocystis causes muscle
       diseases and also abortion or myeloencephalitis with lethal outcome in
       certain animal species. Molecular-epidemiological investigations have
       resulted in a new understanding of biological and population-genetic
       mechanisms relevant to the disease. Recently developed molecular
       techniques, such as transfection in protozoan parasites, are presently
       used not only to elucidate molecular-pathogenetic events in the course
       of disease, but also to prepare potential new immuno-therapeutic tools
       for future vaccination against infection or disease.
 DE    Animal  Coccidiosis/EPIDEMIOLOGY/*PARASITOLOGY/*VETERINARY  English
       Abstract  Epidemiology, Molecular  Human  Infant, Newborn  Neospora
       Sarcocystosis/EPIDEMIOLOGY/PARASITOLOGY/VETERINARY  Toxoplasma
       Toxoplasmosis/EPIDEMIOLOGY/PARASITOLOGY  Toxoplasmosis,
       Animal/EPIDEMIOLOGY/PARASITOLOGY  Toxoplasmosis, Congenital/PARASITOLOGY
       Zoonoses  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

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