Document 0744
 DOCN  M9590744
 TI    [Diagnosis of colitis caused by cytomegalovirus infection in AIDS.
       Comparative value of total colonoscopy and rectosigmoidoscopy (apropos
       of 24 cases). AIDS GIT]
 DT    9509
 AU    Combes R; Vallot T; Marche C; Pepin P; Bouchaud O; Verdon R; Longuet P;
       Mignon M; Rene E; CHU Bichat-Claude Bernard, Paris.
 SO    Presse Med. 1995 Mar 25;24(12):572-6. Unique Identifier : AIDSLINE
       MED/95288225
 AB    OBJECTIVES: To evaluate the respective diagnostic value of flexible
       rectosigmoidoscopy and colonoscopy in the cytomegalovirus colitis.
       METHODS: Twenty-four patients with AIDS were studied retrospectively.
       The entry criteria were: flexible rectosigmoidoscopy or colonoscopy,
       with 2 rectal and 2 caecal biopsies, presenting cytomegalovirus
       inclusions bodies linked to an inflammation at least on one colonic
       biopsy. RESULTS: Twenty-four patients had 29 colonoscopies. In 16 cases
       colonoscopy was performed to the caecum. The endoscopic findings of the
       16 full colonoscopies were: 7 right colitis, 5 diffuse colitis, 2
       bisegmentary colitis, 1 proctitis and 1 non endoscopic lesion. The
       histologic findings of the 16 full colonoscopies were: 5 cytomegalovirus
       inclusions on rectal biopsies and 16 on caecal biopsies. For the 13
       incomplete colonoscopies, 11 had inclusions on rectal biopsies. So the
       flexible rectosigmoidoscopy was not sufficient to find inclusions 13
       times out of 29. CONCLUSION: Our study indicates that in the
       cytomegalovirus colitis, inclusions predominate in the caecum, isolated
       right colitis exists and extra-colonic cytomegalovirus disease is not
       always found. For these reasons full colonoscopy is necessary for
       diagnosis in patients with normal flexible rectosigmoidoscopy.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult  AIDS-Related
       Opportunistic Infections/COMPLICATIONS/RADIOGRAPHY/  VIROLOGY
       Colitis/*ETIOLOGY/RADIOGRAPHY/VIROLOGY  Colonoscopy/*METHODS
       Comparative Study  Cytomegalovirus
       Infections/*COMPLICATIONS/RADIOGRAPHY/VIROLOGY  English Abstract  Female
       Human  Male  Middle Age  Retrospective Studies  Sigmoidoscopy/*METHODS
       JOURNAL ARTICLE

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