Document 1096 DOCN M9591096 TI Tropical spastic paraparesis occurring in HTLV-1 associated infective dermatitis. Report of two cases. DT 9509 AU LaGrenade L; Morgan C; Carberry C; Hanchard B; Fletcher V; Gray R; Cranston B; Rodgers-Johnson P; Manns A; Department of Medicine, U.W.I., Jamaica. SO West Indian Med J. 1995 Mar;44(1):34-5. Unique Identifier : AIDSLINE MED/95313397 AB An association between HTLV-1 infection and infective dermatitis (ID) a relapsing eczematous condition of Jamaican children, was reported in 1990. These patients are at risk of developing other known HTLV-1 related diseases. We have observed the development of HTLV-1 associated myelopathy/tropical spastic paraparesis in two patients, ages 14 and 35 years, who were diagnosed with ID at ages 2 and 10 years, respectively. Infective dermatitis of children serves as an early marker of HTLV-I infection and may predict later development of either the malignant outcome, adult T-cell leukaemia/lymphoma or the neurologic manifestation HAM/TSP among adult carriers of HTLV-1 infection. DE Adolescence Adult Case Report Child, Preschool Chronic Disease Female Follow-Up Studies Human HTLV-I Infections/*DIAGNOSIS Jamaica Paraparesis, Tropical Spastic/*DIAGNOSIS Skin Diseases, Bacterial/*DIAGNOSIS Staphylococcal Skin Infections/DIAGNOSIS Streptococcal Infections/DIAGNOSIS Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).