Document 1191 DOCN M9591191 TI [Application of T-subgroup cells assay in the immunology of oral-maxillofacial cancer] DT 9509 AU Lu C; Yin D; Cao D; School of stomatology, Shanghai Second Medical University. SO Chung Hua Kou Chiang Hsueh Tsa Chih. 1995 Jan;30(1):29-31, 64. Unique Identifier : AIDSLINE MED/95309080 AB We report on T-subgroup cells in 70 cases of oral-maxillofacial cancer determined by T-monoclone antibody-OKT system. The results are as follows: CD3, CD4/CD8 value of cancer patients was decreased significantly, compared with that of health or oral benign tumor patients. CD8 was significantly increased (P < 0.001); however, CD8 was decreased and CD4/CD8 ratio was increased after operation. 20 cases underwent the dynamic testing, determined in 1 week, 1 and 3 month. The results are as follows: CD3, CD4, CD4/CD8 values were increased gradually and CD8 was decreased gradually in 17 cases of curative patients, but CD4, CD4/CD8, values were decreased and CD8 was increased significantly in 3 cases of metastased patients. Our conclusion is that determination of T-subgroup cells is of reference value for monitoring and treating cancer patients. DE Adenocarcinoma/IMMUNOLOGY Adult Carcinoma, Squamous Cell/IMMUNOLOGY CD4-CD8 Ratio English Abstract Facial Neoplasms/*IMMUNOLOGY Female Human Male Middle Age Mouth Neoplasms/*IMMUNOLOGY T-Lymphocyte Subsets/*IMMUNOLOGY JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).