Document 1226
 DOCN  M9591226
 TI    Polyarthritis in HTLV-1-infected patients. A review of 17 cases.
 DT    9509
 AU    Guerin B; Arfi S; Numeric P; Jean-Baptiste G; Le Parc JM; Smadja D;
       Grollier-Bois L; Department of Medicine and Rheumatology, Teaching
       Hospital,; Fort-de-France, Martinique.
 SO    Rev Rhum Engl Ed. 1995 Jan;62(1):21-8. Unique Identifier : AIDSLINE
       MED/95308071
 AB    A retrospective study was conducted in Martinique to identify patients
       with polyarthritis and positive serologic tests for the human T-cell
       lymphotropic virus Type I (HTLV-1). Patients with metabolic or bacterial
       causes of polyarthritis were excluded. We found 17 cases of
       HTLV-1-positive polyarthritis (6.7% of the total of polyarthritis
       patients followed in our department); there were 14 females and three
       males, and all the patients were West-Indian blacks. Mean age at
       diagnosis was 50 years. Five patients also had tropical spastic
       paraparesis. The polyarthritis was the inaugural manifestation of T-cell
       leukemia in one patient. Four patients had received blood transfusions.
       Fever, myalgia, and/or skin lesions were present at onset of the
       polyarthritis in seven cases. All 17 patients had peripheral, bilateral,
       symmetric polyarthritis; the most commonly involved sites were the hands
       (17/17) and knees (14/17). Three patients had rheumatoid factor and five
       had antinuclear antibody. Ten patients met at least four American
       Rheumatism Association criteria for rheumatoid arthritis; they accounted
       for 6.7% (10/150) of all polyarthritis patients managed in the same
       hospital department during the same period. We compared these ten
       patients with 20 HTLV-1-negative rheumatoid arthritis patients matched
       on gender, ethnic origin, and disease duration. There were no
       significant differences between the two groups for any of the parameters
       studied.
 DE    Adult  Aged  Antigen-Antibody Reactions  Arthritis/*VIROLOGY  Arthritis,
       Rheumatoid/DIAGNOSIS/IMMUNOLOGY/VIROLOGY  Child, Preschool  Comparative
       Study  Female  Human  *HTLV-BLV Infections  *HTLV-I  Male  Middle Age
       Retrospective Studies  JOURNAL ARTICLE

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