Document 1245
 DOCN  M9591245
 TI    [AIDS. Hypothesis on the origin and emergence of HIV]
 DT    9509
 AU    Verdrager J
 SO    Bull Soc Pathol Exot. 1995;88(1):54-9; discussion 59-60. Unique
       Identifier : AIDSLINE MED/95307127
 AB    Cross-species transfer of simian immunodeficiency viruses (SIV) may
       occur accidentally. This transfer, with the possible exception of the
       virus of the sooty mangabey monkey, leads to a biological dead-end.
       Thus, only serial passages of the virus from man to man, through blood
       inoculation, could explain its progressive evolution from SIV to HIV.
       Such an artificial cycle may have been initiated, in the 1910s,
       following the introduction of syringes and needles into the region of
       the African Great Lakes, a region where some communities were
       considering that the inoculation of blood from certain individuals or
       from monkeys was a very powerful magical remedy. The first HIV-1
       infection may have emerged in the 1940s, in one of these isolated
       communities among which the virus remained at first confined before
       spreading to other populations.
 DE    Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY/*TRANSMISSION  Africa
       Animal  English Abstract  Human  *HIV  HIV-1  HIV-2  *Models, Biological
       Simian Acquired Immunodeficiency Syndrome/TRANSMISSION  SIV  JOURNAL
       ARTICLE

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