Document 1252
 DOCN  M9591252
 TI    Congenital infection.
 DT    9509
 AU    Henderson JL; Weiner CP; Department of Obstetrics and Gynecology,
       University of Iowa; Hospitals and Clinics, Iowa City, USA.
 SO    Curr Opin Obstet Gynecol. 1995 Apr;7(2):130-4. Unique Identifier :
       AIDSLINE MED/95306723
 AB    The past year has shed much new light on congenital infection. A key
       development has been the application of polymerase chain reaction
       technology to the diagnosis of intrauterine infection. This technique
       appears to be the diagnostic tool of choice for toxoplasmosis and
       cytomegalovirus. Pharmacologic treatment appears to reduce the sequellae
       of toxoplasmosis when treated either in utero or postnatally. Obstetric
       interventions may reduce vertical transmission. Education has been shown
       to reduce the incidence of seroconversion for toxoplasmosis, and
       HIV-positive women treated with zidovudine have a dramatically reduced
       rate of transmission to their offspring.
 DE    Chickenpox/*CONGENITAL/DIAGNOSIS/THERAPY  Cytomegalovirus
       Infections/*CONGENITAL/DIAGNOSIS/PREVENTION &  CONTROL/THERAPY  Disease
       Transmission, Vertical/PREVENTION & CONTROL  Female  Fetal
       Diseases/DIAGNOSIS/PREVENTION & CONTROL/THERAPY  Human  Infant, Newborn
       Pregnancy  *Toxoplasmosis, Congenital/DIAGNOSIS/PREVENTION &
       CONTROL/THERAPY  JOURNAL ARTICLE  REVIEW  REVIEW LITERATURE

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