Document 0004
 DOCN  M95A0004
 TI    Reversible acute renal failure due to sulfonamide-induced lithiasis in
       an AIDS patient.
 DT    9510
 AU    Farina LA; Palou Redorta J; Chechile Toniolo G; Urology Department,
       Fundacion Puigvert, Barcelona, Spain.
 SO    Arch Esp Urol. 1995 May;48(4):418-9. Unique Identifier : AIDSLINE
       MED/95321782
 AB    OBJECTIVE: Drug-induced lithiasis was well-known some years ago, when
       sulfonamides poorly soluble in urine were in use. Now, they are again in
       use for some opportunistic AIDS-related infections. We report herein the
       case of an AIDS patient, treated with sulfadiazine because of Nocardia
       pneumonia, that came to the emergency room in acute renal failure.
       METHODS/RESULTS: Obstructive uropathy due to radiolucent calculi was
       suspected and retrograde ureteral catheterization was necessary. The
       calculi recovered were identified as N-acetyl sulfadiazine by infrared
       spectrophotometry. CONCLUSION: Rapid improvement can be achieved in
       these patients when the drug is discontinued or decrease and systemic
       fluid and urine alkalinization are started.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult  AIDS-Related
       Opportunistic Infections/COMPLICATIONS/DRUG THERAPY  Case Report  Human
       *HIV-1  Kidney Calculi/*CHEMICALLY INDUCED/DIAGNOSIS  Kidney Failure,
       Acute/*CHEMICALLY INDUCED/DIAGNOSIS  Male  Nocardia
       Infections/COMPLICATIONS/DRUG THERAPY  Pneumonia,
       Bacterial/COMPLICATIONS/DRUG THERAPY  Sulfadiazine/ADMINISTRATION &
       DOSAGE/*ADVERSE EFFECTS  JOURNAL ARTICLE  REVIEW  REVIEW OF REPORTED
       CASES

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