Document 0021
 DOCN  M95A0021
 TI    Recovery of Pseudomonas aeruginosa in respiratory specimens from HIV
       positive patients being evaluated for Pneumocystis carinii pneumonia.
 DT    9510
 AU    Doyle RL; Doherty JJ; Zimmerman LH; Cardiovascular Research Institute,
       University of California at; San Francisco, USA.
 SO    Thorax. 1995 May;50(5):548-50. Unique Identifier : AIDSLINE MED/95320833
 AB    BACKGROUND--Despite the immune suppression, frequent hospital
       admissions, and many intercurrent illnesses associated with HIV
       infection, Pseudomonas aeruginosa has been cited relatively infrequently
       as a respiratory pathogen in HIV positive patients. METHODS--The
       microbiological isolates, medical records, radiographic reports, and
       laboratory data from 224 patients undergoing sputum induction and/or
       bronchoalveolar lavage for evaluation of respiratory symptoms suspicious
       for Pneumocystis carinii pneumonia (PCP) from 1989 to 1992 were reviewed
       retrospectively. RESULTS--An increasing number of respiratory isolates
       with Pseudomonas aeruginosa was found over this time period. Eighteen of
       the 224 patients were identified in whom P aeruginosa was recovered on
       at least one occasion. These patients were more likely to have a history
       of smoking and prior PCP than those in whom Pseudomonas was not
       recovered. Mean CD4 counts were also significantly lower in these
       patients. CONCLUSIONS--Pseudomonas aeruginosa may be recovered from a
       substantial number of respiratory isolates from HIV positive patients
       suspected of having PCP. The prevalence of this phenomenon may be
       increasing.
 DE    Bronchoalveolar Lavage Fluid/*MICROBIOLOGY  CD4 Lymphocyte Count  Female
       Human  HIV Infections/*COMPLICATIONS/IMMUNOLOGY/MICROBIOLOGY  Male
       Pneumonia, Pneumocystis carinii/MICROBIOLOGY  Pseudomonas
       Infections/COMPLICATIONS/IMMUNOLOGY/*MICROBIOLOGY  Retrospective Studies
       Smoking  Sputum/*MICROBIOLOGY  JOURNAL ARTICLE

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