Document 0105
 DOCN  M95A0105
 TI    Seroprevalence of human T cell lymphotropic virus type II infection,
       with or without human immunodeficiency virus type 1 coinfection, among
       US intravenous drug users.
 DT    9510
 AU    Briggs NC; Battjes RJ; Cantor KP; Blattner WA; Yellin FM; Wilson S; Ritz
       AL; Weiss SH; Goedert JJ; National Cancer Institute, National Institute
       on Drug Abuse,; National Institutes of Health, Bethesda, Maryland, USA.
 SO    J Infect Dis. 1995 Jul;172(1):51-8. Unique Identifier : AIDSLINE
       MED/95318559
 AB    Seroprevalence of human T lymphotropic virus (HTLV) and human
       immunodeficiency virus type 1 (HIV-1) was determined among 7841
       intravenous drug users (IVDUs) from drug treatment centers in Baltimore,
       Chicago, Los Angeles, New Jersey (Asbury Park and Trenton), New York
       City (Brooklyn and Harlem), Philadelphia, and San Antonio, Texas; 20.9%
       had evidence of HTLV infection, as determined using a p21e EIA for
       screening and p21e blot for confirmation. With a type-specific EIA and
       blot used in combination, HTLV-II was identified in 97.6% of
       HTLV-positive IVDUs whose sera could be subtyped. HIV-1 seroprevalence
       was 13.2%. HTLV-II without HIV-1 was most common in Los Angeles and San
       Antonio. HIV-1 without HTLV-II was most common in New York, New Jersey,
       and Baltimore. Dual infection was most common in New York and New
       Jersey. Logistic regression analysis revealed that seroprevalence of
       HTLV-II was significantly greater with HIV-1 infection and increasing
       age and among women, blacks, and Mexican-Americans. In conclusion, it
       appears that among US IVDUs, nearly all HTLV infection is attributable
       to HTLV-II, and HTLV-II infection is associated with HIV-1 and
       sociodemographic background.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/*EPIDEMIOLOGY
       Adolescence  Adult  Age Factors  Blacks  Comparative Study  Demography
       Ethnic Groups  Female  Human  HIV Antibodies/BLOOD  HIV
       Infections/*COMPLICATIONS/*EPIDEMIOLOGY  HIV Seroprevalence  HIV-1
       HTLV-II Antibodies/BLOOD  HTLV-II
       Infections/*COMPLICATIONS/*EPIDEMIOLOGY  Male  Mexican Americans  Racial
       Stocks  Sex Factors  *Substance Abuse, Intravenous  Support, U.S. Gov't,
       P.H.S.  United States/EPIDEMIOLOGY  Urban Population  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).