Document 0176
 DOCN  M95A0176
 TI    IgA antiphospholipid antibodies in HTLV-1-associated tropical spastic
       paraparesis.
 DT    9510
 AU    Wilson WA; Morgan Ost C; Barton EN; Smikle M; Hanchard B; Blattner WA;
       Doggett S; Gharavi AE; Department of Medicine, Lousiana State University
       Medical Center,; New Orleans 70112, USA.
 SO    Lupus. 1995 Apr;4(2):138-41. Unique Identifier : AIDSLINE MED/95315960
 AB    A retrovirus, human T cell lymphotropic virus type 1 (HTLV-1), is an
       essential but not a sufficient aetiologic factor for tropical spastic
       paraparesis (TSP). Because some TSP patients have biological false
       positive tests for treponemal infections (BFP-STS), we used ELISA to
       study BFP-STS and anticardiolipin antibodies in 42 Jamaican TSP
       patients. The data indicate that in TSP anticardiolipin antibodies occur
       in about 26% of patients, are associated with biological false positive
       treponemal serology, are relatively restricted to the IgA isotype and
       may be induced by HTLV-1 or other nontreponemal infections.
 DE    Adult  Aged  Antibodies, Antiphospholipid/*BLOOD  Female  Human
       IgA/*BLOOD  Male  Middle Age  Paraparesis, Tropical Spastic/*IMMUNOLOGY
       Treponemal Infections/DIAGNOSIS  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).