Document 0201
 DOCN  M95A0201
 TI    Early intervention for persons infected with human immunodeficiency
       virus.
 DT    9510
 AU    Branson BM; Division of STD/HIV Prevention, Centers for Disease Control
       and; Prevention, Atlanta, Georgia 30333, USA.
 SO    Clin Infect Dis. 1995 Apr;20 Suppl 1:S3-22. Unique Identifier : AIDSLINE
       MED/95315411
 AB    Early intervention for persons infected with human immunodeficiency
       virus (HIV) involves characterization of the stage of HIV disease,
       institution of therapy to prevent associated infections and postpone
       deterioration of immune function, and assistance in preventing
       transmission of the virus. This review examines the available data on
       the efficacy of current recommendations regarding the evaluation and
       management of persons with early HIV infection. Existing evidence
       supports the efficacy of physical examination, monitoring of the CD4+
       cell count, tuberculin testing (with chemotherapy for persons who test
       positive), anergy testing, Papanicolaou testing and screening for
       gonorrhea and chlamydial infection (for high-risk women), screening for
       syphilis, antiretroviral therapy (for symptomatic patients), and
       guidance in reducing the transmission of HIV. Recommended measures for
       which evidence of clinical efficacy is less certain include immunization
       against infections due to influenza virus, Streptococcus pneumoniae,
       Haemophilus influenzae, and hepatitis B virus as well as antiretroviral
       therapy for asymptomatic persons. Quantitative measurement of viral
       titers appears promising for the monitoring of HIV disease and
       antiretroviral therapy; the correlations of these titers with clinical
       end points need to be confirmed.
 DE    Human  HIV Infections/*DIAGNOSIS/EPIDEMIOLOGY/*THERAPY/TRANSMISSION
       Monitoring, Physiologic  Time Factors  JOURNAL ARTICLE  REVIEW  REVIEW,
       TUTORIAL

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