Document 0202
 DOCN  M95A0202
 TI    Treatment of syphilis, 1993.
 DT    9510
 AU    Rolfs RT; Division of STD/HIV Prevention, Centers for Disease Control
       and; Prevention, Atlanta, Georgia 30333, USA.
 SO    Clin Infect Dis. 1995 Apr;20 Suppl 1:S23-38. Unique Identifier :
       AIDSLINE MED/95315410
 AB    Data on treatment of patients with syphilis were reviewed in preparation
       for revision of the Sexually Transmitted Disease Treatment Guidelines of
       the Centers for Disease Control and Prevention. Published studies of
       treatment regimens available and practical for use today were reviewed,
       particularly in regard to the following issues: treatment for primary,
       secondary, and latent stages of syphilis; treatment for syphilis during
       pregnancy; treatment for syphilis in human immunodeficiency virus
       (HIV)-infected patients; and serological criteria for evaluating
       response to treatment. The results of treatment and the methodological
       quality of the studies was considered. Most treatment recommendations
       must be based on expert judgment and with reliance on the clinical
       experience over 4 decades. For the treatment of early syphilis in
       HIV-uninfected patients, this is probably sufficient. Data about
       HIV-infected patients are insufficient both for determining whether
       current therapy is adequate and for recommendation of an alternative if
       a change in therapy is deemed necessary.
 DE    Female  Follow-Up Studies  Human  HIV Infections/COMPLICATIONS  Male
       Penicillins/THERAPEUTIC USE  Pregnancy  Pregnancy Complications,
       Infectious/DRUG THERAPY  Syphilis/COMPLICATIONS/*DRUG THERAPY  JOURNAL
       ARTICLE  REVIEW  REVIEW, TUTORIAL

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       protected by Copyright Law (Title 17, U.S.Code).