Document 0208 DOCN M95A0208 TI Isolated peripheral tuberculous lymphadenitis in adults: current clinical and diagnostic issues. DT 9510 AU Artenstein AW; Kim JH; Williams WJ; Chung RC; Division of Retrovirology, Walter Reed Army Institute of; Research, Rockville, Maryland 20850, USA. SO Clin Infect Dis. 1995 Apr;20(4):876-82. Unique Identifier : AIDSLINE MED/95315391 AB Eight cases of isolated peripheral tuberculous lymphadenitis occurred over a 16-month period at our institution, prompting a literature review to establish the epidemiology, clinical manifestations, and current approaches to diagnosis and treatment of this disorder. It occurs most commonly in young adult women who either are immigrants from areas where tuberculous is endemic or have histories of travel that are suggestive of exposure to Mycobacterium tuberculosis. The disease is indolent and usually presents as a unilateral painless neck mass. Constitutional symptoms are rare, except in individuals infected with the human immunodeficiency virus (HIV). The results of skin testing with purified protein derivative are invariably positive. Excisional biopsy for histopathologic and microbiological evaluations provides the highest diagnostic yield, although fine needle aspiration may be useful for HIV-infected individuals and in areas of the world with a high prevalence of disease. A 6-month course of combination antituberculous therapy is adequate for disease due to susceptible organisms. This infection may be readily diagnosed if suggestive epidemiological and clinical findings lead to expeditious tissue sampling. DE Adult Algorithms Case Report Female Human Male Middle Age *Tuberculosis, Lymph Node/DIAGNOSIS/EPIDEMIOLOGY/MICROBIOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).