Document 0213
 DOCN  M95A0213
 TI    Cytomegalovirus infections of the nervous system in patients with AIDS.
 DT    9510
 AU    McCutchan JA; Department of Medicine, UCSD School of Medicine, USA.
 SO    Clin Infect Dis. 1995 Apr;20(4):747-54. Unique Identifier : AIDSLINE
       MED/95315370
 AB    Retinitis due to cytomegalovirus (CMV) infection is a widely recognized
       complication of advanced disease due to human immunodeficiency virus
       type 1 (HIV-1). Less appreciated are other neurological manifestations
       of CMV infection in persons with AIDS. Dr. J. Allen McCutchan has
       comprehensively reviewed the various clinical presentations of CMV
       neurological disease as well as the methods of diagnosis, the
       neuropharmacology of available antiviral agents, the results of therapy,
       and the potential for prevention of these sequela of advanced
       immunosuppression. As the ability to prevent diseases such as
       Pneumocystis carinii pneumonia, bacteremia secondary to Mycobacterium
       avium, tuberculosis, serious fungal infections, and toxoplasma
       cerebritis is increasing, physicians must now treat more HIV-1-infected
       persons with CMV disease. This AIDS Commentary provides a timely update
       of the current state of our knowledge regarding this serious problem.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Cerebral Ventricles
       Cognition Disorders/VIROLOGY  Cytomegalovirus
       Infections/*COMPLICATIONS/DRUG THERAPY  Cytomegalovirus
       Retinitis/COMPLICATIONS  Dementia/VIROLOGY  Encephalitis, Viral/VIROLOGY
       Forecasting  Human  Movement Disorders/VIROLOGY  Nervous System
       Diseases/DRUG THERAPY/*VIROLOGY  Neuritis/VIROLOGY  Support, Non-U.S.
       Gov't  Support, U.S. Gov't, P.H.S.  JOURNAL ARTICLE  REVIEW  REVIEW,
       TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).