Document 0219 DOCN M95A0219 TI Bartonella (Rochalimaea) species as a cause of apparent culture-negative endocarditis. DT 9510 AU Spach DH; Kanter AS; Daniels NA; Nowowiejski DJ; Larson AM; Schmidt RA; Swaminathan B; Brenner DJ; Department of Medicine, University of Washington Medical Center,; University of Washington School of Medicine, Seattle, USA. SO Clin Infect Dis. 1995 Apr;20(4):1044-7. Unique Identifier : AIDSLINE MED/95315349 AB Bartonella quintana (formerly Rochalimaea quintana) is a recently recognized cause of apparent culture-negative endocarditis. We describe a 39-year-old, homeless man who developed aortic valve endocarditis caused by B. quintana. He had a history of alcoholism and was seronegative for the human immunodeficiency virus. We established that B. quintana was the cause of the endocarditis on the basis of the isolation of B. quintana from blood cultures, the compatibility of histochemical stains of cardiac valve tissue, the reactivity of the polymerase chain reaction specific for B. quintana on cardiac valve tissue, and the failure to isolate an alternative causative organism despite extensive efforts. This is the second report of endocarditis caused by B. quintana and the fourth report of endocarditis caused by a Bartonella species. On the basis of the findings of this report and those of other recent reports, further study is warranted to determine the overall role of Bartonella species in apparent culture-negative endocarditis. DE Adult *Aortic Valve/MICROBIOLOGY Bartonella/ISOLATION & PURIF *Bartonella Infections/MICROBIOLOGY Case Report Endocarditis, Bacterial/*MICROBIOLOGY False Negative Reactions Heart Valve Diseases/MICROBIOLOGY Human Male JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASES SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).