Document 0285
 DOCN  M95A0285
 TI    Spread of maternal HIV infection in Scotland from 1990 to 1992.
 DT    9510
 AU    Tappin DM; Johnstone FD; Smith R; Girdwood RW; Follett EA; Davidson CF;
       Department of Child Health, Royal Hospital for Sick Children,; Glasgow.
 SO    Scott Med J. 1995 Feb;40(1):12-4. Unique Identifier : AIDSLINE
       MED/95327900
 AB    In Scotland since January 1990, unlinked anonymous testing of Guthrie
       cards has documented maternal HIV-1 antibody in neonatal blood. District
       postcode and quarter year of birth determined prevalence and spread of
       infection. The Fujirebio particle agglutination assay screened for HIV-1
       antibody, with confirmation by ELISA and full western blotting. Births
       to known HIV infected women were reported to the Royal College of
       Obstetricians and Gynaecologists. 0.3/1000 childbearing women were
       infected with HIV-1 with no significant increase from 1990 to 1992.
       Spread of infection from 11 to 26 districts has occurred. In 1990,
       74%(14/19) of HIV positive deliveries were known to obstetricians
       falling to 33%(7/21) in 1992. Spread of HIV-1 infection has occurred to
       mothers who live outside closely defined areas and who do not belong to
       recognised high risk groups. In Scotland, two thirds of mothers and
       their infants will not receive early prophylactic care for their HIV
       disease.
 DE    AIDS Serodiagnosis  *Disease Transmission, Vertical  Female  Human  HIV
       Antibodies/BLOOD  HIV Infections/DIAGNOSIS/*EPIDEMIOLOGY/IMMUNOLOGY
       Immunity, Maternally-Acquired  Incidence  Infant, Newborn  Mothers
       Pregnancy  Scotland/EPIDEMIOLOGY  Support, Non-U.S. Gov't  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).