Document 0637
 DOCN  M95A0637
 TI    Prediction of pediatric neuro-AIDS. American Pediatric Society 104th
       annual meeting and Society for Pediatric Research 63rd annual meeting;
       1994 May 2-5; Seattle.
 DT    9510
 AU    Wachtel RC; Tepper VJ; Farley J; Houck D; Vink P; University of Maryland
       School of Medicine, Department of; Pediatrics, Baltimore, USA.
 SO    Pediatr AIDS HIV Infect. 1994 Oct;5(5):315 (unnumbered abstract). Unique
       Identifier : AIDSLINE AIDS/95330407
 AB    As part of a longitudinal study of 35 vertically HIV-infected infants,
       laboratory data at 6 months of age were compared to Bayley Scales of
       Infant Development scores (MDI & PDI) at 12 and 24 months of age using
       bivariate linear regression. Highly significant predictive relationships
       were found between absolute lymphocyte counts (ALC), CD4 and CD8 counts
       and later developmental function, with the CD4 being the most robust.
       Results suggest that a defect in immune surveillance is an important
       component of pediatric neuro-AIDS. TABULAR DATA, SEE PUBLISHED ABSTRACT.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/IMMUNOLOGY  Child,
       Preschool  CD4 Lymphocyte Count  CD8-Positive T-Lymphocytes  Human
       Infant  Lymphocyte Count  Nervous System
       Diseases/*COMPLICATIONS/IMMUNOLOGY  Predictive Value of Tests  MEETING
       ABSTRACT  JOURNAL ARTICLE

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