Document 0663
 DOCN  M95A0663
 TI    Herpes cancer? 
 DT    9510
 SO    Treat Rev. 1995 Mar/Apr;(no 17):3. Unique Identifier : AIDSLINE
       AIDS/95700320
 AB    Two researchers have announced there is strong evidence that Kaposi's
       sarcoma (KS) is actually caused by a newly recognized herpes virus which
       is called KSHV. Herpesviruses have long been suspected as co-factors in
       HIV disease, although before now they have not been linked to KS.
       Another group of scientists suggests that HIV causes the body to produce
       chemicals that create a hospitable environment for KS to grow. Both
       groups could be right. What is known about treating KS is that the drugs
       currently used are not always effective and are costly and toxic.
       Rapidly executed clinical trials are needed to determine whether new
       drugs like Doxil, the anti-herpes drugs foscarnet and acyclovir, or the
       Abbott protease inhibitor, are useful in treating KS.
 DE    AIDS-Related Opportunistic Infections/*VIROLOGY  Acyclovir/THERAPEUTIC
       USE  Foscarnet/THERAPEUTIC USE  Herpesviridae/*PATHOGENICITY  Human
       Sarcoma, Kaposi's/DRUG THERAPY/*VIROLOGY  NEWSLETTER ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).