Document 0753
 DOCN  M95A0753
 TI    AIDS-related cholangitis: diagnostic features and course in four
       patients.
 DT    9510
 AU    Bird GL; Kennedy DH; Forrest JA; Department of Gastroenterology,
       Stobhill General Hospital,; Glasgow.
 SO    Scott Med J. 1995 Apr;40(2):53-4. Unique Identifier : AIDSLINE
       MED/95343329
 AB    Radiological features of sclerosing cholangitis are an uncommon but well
       recognised complication of HIV infection in homosexual males. In this
       report we document the clinical features and course of the disease in
       four patients. Four homosexual males with established AIDS were referred
       in 1990-92. Three of the four had intractable upper abdominal pain which
       was poorly responsive to opiates. Three of the patients had diarrhoea
       and all had weight loss. The diagnosis of AIDS related cholangitis was
       confirmed by endoscopic retrograde cholangiography in three cases, but
       in only one patient was there no evidence of biliary disease on
       ultrasound scanning. In the two cases with cholangiographic features of
       papillary stenosis, endoscopic sphincterotomy was carried out and there
       was subsequently a dramatic improvement in the abdominal pain. Three of
       the patients had evidence of gastrointestinal infection with
       Microsporidia (1) or Cryptosporidia (2). All the patients died within
       2-9 months of the diagnosis of cholangitis, but none of the deaths
       resulted from hepatobiliary disease.
 DE    Adult  AIDS-Related Opportunistic Infections/BLOOD/*DIAGNOSIS/SURGERY
       Case Report  Cholangiopancreatography, Endoscopic Retrograde
       Cholangitis, Sclerosing/BLOOD/*DIAGNOSIS/SURGERY/VIROLOGY  Fatal Outcome
       Homosexuality, Male  Human  Liver Function Tests  Male  Sphincterotomy,
       Endoscopic  JOURNAL ARTICLE

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