Document 0757
 DOCN  M95A0757
 TI    Invasive pulmonary aspergillosis in AIDS: radiographic, CT, and
       pathologic findings.
 DT    9510
 AU    Staples CA; Kang EY; Wright JL; Phillips P; Muller NL; Department of
       Radiology, University of British Columbia and St; Paul's Hospital,
       Vancouver, Canada.
 SO    Radiology. 1995 Aug;196(2):409-14. Unique Identifier : AIDSLINE
       MED/95343104
 AB    PURPOSE: To review the radiographic and computed tomographic (CT)
       manifestations of invasive pulmonary aspergillosis and to correlate the
       imaging and pathologic findings in patients with acquired
       immunodeficiency syndrome (AIDS). MATERIALS AND METHODS: Chest
       radiographs, CT scans, and pathologic specimens were reviewed
       retrospectively in 10 AIDS patients with proved invasive pulmonary
       aspergillosis. RESULTS: The most common radiographic finding was the
       presence of thick-walled cavitary lesions. Less common findings included
       nodules, consolidation, and pleural effusion. CT depicted more nodules
       and cavities than did radiography. The predominant pathologic
       abnormalities consisted of tissue invasion and abscess formation and
       angioinvasion with or without infarction. All patients had infection
       with Aspergillus fumigatus as well as other pathogens, the most common
       being cytomegalovirus and Pseudomonas aeruginosa. CONCLUSION:
       Thick-walled cavitary lesions are the most common radiologic
       manifestation of invasive pulmonary aspergillosis in AIDS. The findings
       are more numerous and better defined on CT scans. The radiologic
       findings reflect a spectrum of pathologic abnormalities.
 DE    Adult  Aspergillosis/*DIAGNOSIS  Aspergillus fumigatus/*ISOLATION &
       PURIF  AIDS-Related Opportunistic Infections/*DIAGNOSIS/MICROBIOLOGY
       Human  Lung/PATHOLOGY/RADIOGRAPHY  Lung Diseases, Fungal/*DIAGNOSIS
       Male  Retrospective Studies  Tomography, X-Ray Computed  JOURNAL ARTICLE

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