Document 0892 DOCN M95A0892 TI Immunopathogenesis of dilated cardiomyopathies. DT 9510 AU Goldman JH; McKenna WJ; Department of Cardiological Sciences, St. George's Hospital; Medical School, London, UK. SO Curr Opin Cardiol. 1995 May;10(3):306-11. Unique Identifier : AIDSLINE MED/95337536 AB Idiopathic dilated cardiomyopathy is a chronic heart muscle disorder of unknown etiology, but experimental and clinical evidence is accumulating that points to an immune pathogenesis in a subset of patients, and to the potential importance of myosin as an antigen. Most recent developments include evidence of cardiac- and disease-specific autoantibodies in a proportion of patients with dilated cardiomyopathy and their relatives, and the identification of immunogenic epitopes. DE Animal Autoantibodies/ANALYSIS Cardiomyopathy, Congestive/*ETIOLOGY/*IMMUNOLOGY Human HIV Infections/COMPLICATIONS Mice Myosin/IMMUNOLOGY JOURNAL ARTICLE REVIEW REVIEW, ACADEMIC SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).