Document 0894 DOCN M95A0894 TI The endemic mycoses: surgical considerations. DT 9510 AU Johnson PC; Sarosi GA; Department of Internal Medicine, The University of Texas Medical; School, Houston, USA. SO Semin Thorac Cardiovasc Surg. 1995 Apr;7(2):95-103. Unique Identifier : AIDSLINE MED/95337245 AB Surgical consultation is regularly requested for diagnosis and treatment of pulmonary complications of the endemic mycosis, Histoplasma capsulatum, Blastomyces dermatitidis and Coccidioidomycosis immitis, and the yeast Cryptococcus neoformans. All resemble pulmonary malignancies. Histoplasmosis causes pericarditis, mediastinal fibrosis and mediastinal granuloma, which can cause entrapment of vascular structures, the esophagus, and the trachea. Coccidioidomycosis can cause spontaneous pneumothorax and thin wall cavities that can be superinfected with tuberculosis and Aspergillosis. The pathogenesis, diagnosis, and treatment of these organisms are discussed with emphasis on the new oral therapies and complications encountered in persons with human immunodeficiency virus (HIV) infection. DE Antifungal Agents/THERAPEUTIC USE Human Lung Diseases, Fungal/COMPLICATIONS/DIAGNOSIS/EPIDEMIOLOGY/ *SURGERY Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).