Document 0895
 DOCN  M95A0895
 TI    Viral pulmonary infections in thoracic and cardiovascular surgery.
 DT    9510
 AU    Avery RK; Longworth DL; Department of Infectious Diseases, Cleveland
       Clinic Foundation, 1; Clinic Center, OH 44195, USA.
 SO    Semin Thorac Cardiovasc Surg. 1995 Apr;7(2):88-94. Unique Identifier :
       AIDSLINE MED/95337244
 AB    Viral respiratory infections are uncommon causes of pulmonary
       infiltrates in immunocompetent patients who undergo cardiothoracic
       surgery. In winter months, however, influenza can be acquired in the
       community preoperatively or in the hospital setting. The recognition of
       influenza cases is essential to prevent nosocomial transmission.
       Respiratory syncytial virus is also an important pulmonary pathogen in
       pediatric patients who undergo cardiothoracic surgery and may produce
       serious disease in children with underlying pulmonary or congenital
       heart disease. Viral infections of the respiratory tract are important
       causes of morbidity and mortality in heart and lung transplant
       recipients, especially cytomegalovirus (CMV). Other herpes viruses such
       as varicella zoster virus and herpes simplex virus may also occasionally
       involve the lung. Epstein-Barr virus has been incriminated in the
       pathogenesis of post-transplant lymphoproliferative disease, an uncommon
       but severe complication of transplantation. Except for Epstein-Barr
       virus, effective therapy exists for CMV and the other herpes viruses.
       Prophylaxis with ganciclovir is effective in preventing serious CMV
       infections in seropositive heart transplant recipients. However, better
       strategies are needed to prevent primary CMV infection in these
       patients.
 DE    Adenovirus Infections, Human  Cross Infection/VIROLOGY  *Heart Surgery
       Herpesviridae Infections  Human  HIV Infections  Infection Control
       Parainfluenza  *Pneumonia, Viral  Respiratory Syncytial Virus Infections
       Respiratory Tract Infections/*VIROLOGY  *Thoracic Surgery  JOURNAL
       ARTICLE  REVIEW  REVIEW, TUTORIAL

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