Document 0028 DOCN M95B0028 TI [Cytomegalovirus-induced colitis in HIV infection. Considerations on its diagnosis, treatment and complications] DT 9511 AU Sousa AE; Lucas M; Palhano MJ; de Deus J; Damiao J; Victorino RM; Servico de Medicina 2, Patologia Cirurgica e Anatomia; Patologica, Hospital Universitario de Santa Maria, Lisboa. SO Acta Med Port. 1995 Apr;8(4):247-51. Unique Identifier : AIDSLINE MED/95351140 AB The diagnosis of cytomegalovirus intestinal disease in patients with HIV (human immunodeficiency virus) infection frequently raises diagnostic problems in view of the absence of definite pathological, serological or virological markers of active CMV infection. We describe the case of a 47-year-old man with a CMV colitis which illustrates several diagnostic and therapeutic problems and that was complicated by an intestinal perforation. We emphasize that in HIV+ patients with chronic diarrhea, the presence of abdominal pain should suggest the possibility of a CMV colitis and that in such cases a colonoscopy with biopsies of the right colon should be performed, in view of the higher frequency of the typical histopathological changes at this level. On the other hand, this case presented a marked thickening of the colon wall, simulating pseudotumoral images on CAT scans, as recently described in literature. The therapeutic possibilities as well as the complications of CMV colitis are discussed in the context of the occurrence of an ileal perforation, which represents the first report of this complication in Portuguese literature and which had the particularity of having a long survival after surgery in comparison with the previous cases described in international literature. DE AIDS-Related Opportunistic Infections/COMPLICATIONS/*DIAGNOSIS/ SURGERY Biopsy Case Report Colitis/COMPLICATIONS/*DIAGNOSIS/SURGERY Colon/PATHOLOGY/RADIOGRAPHY Colonoscopy Cytomegalovirus Infections/COMPLICATIONS/*DIAGNOSIS/SURGERY English Abstract Human *HIV-1 Ileostomy Male Middle Age Tomography, X-Ray Computed JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASES SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).