Document 0093
 DOCN  M95B0093
 TI    Molecular epidemiology of hepatitis C virus infection amongst
       intravenous drug users in rural communities.
 DT    9511
 AU    Majid A; Holmes R; Desselberger U; Simmonds P; McKee TA; Clinical
       Microbiology and Public Health Laboratory, Addenbrooke's; Hospital,
       Cambridge, United Kingdom.
 SO    J Med Virol. 1995 May;46(1):48-51. Unique Identifier : AIDSLINE
       MED/95348669
 AB    The prevalence of hepatitis C virus (HCV) infection amongst a group of
       intravenous drug users (IVDUs) resident in West Suffolk (East Anglia,
       England) was investigated and compared with the prevalence of infection
       with hepatitis B virus (HBV) and human immunodeficiency virus (HIV). In
       addition, both the level of HCV persistence, as defined by detection of
       viral RNA, and the HCV genotypes present in this population were
       determined. It was found that HCV antibodies were present in 59% of
       those tested; by comparison 22% had antibodies to HBV and 1% antibodies
       to HIV. HCV RNA was found in 44% of those with HCV antibody. HCV
       genotype 1 was the most prevalent within this population although both
       genotypes 2 and 3 were also represented.
 DE    Adolescence  Adult  Base Sequence  Genotype  Great Britain/EPIDEMIOLOGY
       Hepatitis Antibodies/BLOOD  Hepatitis B Antibodies/BLOOD  Hepatitis
       C/COMPLICATIONS/*EPIDEMIOLOGY  Hepatitis C Viruses/CLASSIFICATION  Human
       HIV Antibodies/BLOOD  Middle Age  Molecular Sequence Data  Prevalence
       Rural Population  RNA, Viral/BLOOD  Seroepidemiologic Methods
       Serotyping  Substance Abuse, Intravenous/*COMPLICATIONS/EPIDEMIOLOGY
       JOURNAL ARTICLE

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