Document 0103
 DOCN  M95B0103
 TI    Testing for antibody to human immunodeficiency virus type 1 in a
       population in which mycobacterial diseases are endemic.
 DT    9511
 AU    Sterne JA; Turner AC; Fine PE; Parry JV; Lucas SB; Ponnighaus JM;
       Mkandwire PK; Nyasulu S; Warndorff DK; Communicable Disease Epidemiology
       Unit, London School of Hygiene; and Tropical Medicine, United Kingdom.
 SO    J Infect Dis. 1995 Aug;172(2):543-6. Unique Identifier : AIDSLINE
       MED/95348558
 AB    During a large epidemiologic study in the Karonga District of northern
       Malawi, serum samples from 139 patients with incident leprosy, 124 with
       newly diagnosed leprosy, 277 patients with incident tuberculosis, and
       2296 controls were tested for antibodies to human immunodeficiency
       virus. Sera were tested according to a four-test protocol using two
       ELISAs and two particle agglutination assays. Overall, 188 samples were
       considered positive, 2634 were considered negative, and 14 were
       indeterminate. All 18 available positive specimens from leprosy
       patients, a random sample of 14 positive specimens from tuberculosis
       patients, and 15 positive specimens from controls were tested by Western
       blot. There was no evidence of substantial numbers of ELISA
       false-positives in any patient group or among controls.
 DE    Adult  Antibodies, Viral/*BLOOD  Case-Control Studies  False Positive
       Reactions  Female  Human  HIV Seronegativity  HIV
       Seropositivity/COMPLICATIONS/EPIDEMIOLOGY/*VIROLOGY
       HIV-1/*IMMUNOLOGY/ISOLATION & PURIF
       Leprosy/COMPLICATIONS/EPIDEMIOLOGY/*VIROLOGY  Malawi/EPIDEMIOLOGY  Male
       Serodiagnosis  Support, Non-U.S. Gov't
       Tuberculosis/COMPLICATIONS/EPIDEMIOLOGY/*VIROLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).