Document 0164 DOCN M95B0164 TI Oral histoplasmosis in HIV-infected patients. A report of two cases. DT 9511 AU Chinn H; Chernoff DN; Migliorati CA; Silverman S Jr; Green TL; Division of Oral Medicine, UCSF, USA. SO Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Jun;79(6):710-4. Unique Identifier : AIDSLINE MED/95346458 AB Histoplasmosis is a fungal infection caused by the organism Histoplasma capsulatum. Disseminated disease usually occurs in immunosuppressed patients or in patients with chronic illnesses. Although relatively uncommon, histoplasmosis has been reported in patients with AIDS, and oral lesions have been noted on multiple sites and in various clinical presentations. We present two HIV-positive cases with oral lesions as the initial signs of histoplasmosis. Both patients responded well to IV amphotericin B but later suffered recurrences despite being maintained on systemic antifungal therapy. DE Adult Amphotericin B/THERAPEUTIC USE AIDS-Related Opportunistic Infections/DRUG THERAPY/*MICROBIOLOGY Case Report Histoplasmosis/DRUG THERAPY/*ETIOLOGY Human HIV Infections/*COMPLICATIONS Ketoconazole/THERAPEUTIC USE Male Mouth Diseases/DRUG THERAPY/*ETIOLOGY/MICROBIOLOGY JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).