Document 0185
 DOCN  M95B0185
 TI    Mycobacterium xenopi infection masquerading as pulmonary tuberculosis in
       two patients infected with the human immunodeficiency virus.
 DT    9511
 AU    Jacoby HM; Jiva TM; Kaminski DA; Weymouth LA; Portmore AC; Division of
       Infectious Diseases, University of Rochester Medical; Center, New York,
       USA.
 SO    Clin Infect Dis. 1995 May;20(5):1399-401. Unique Identifier : AIDSLINE
       MED/95345320
 AB    Mycobacterium xenopi infections have rarely been reported among patients
       infected with the human immunodeficiency virus (HIV). We recently
       treated two HIV-infected men, neither of whom had a history of pulmonary
       disease or AIDS-defining conditions, and who had M. xenopi lung
       infections. Both patients presented with night sweats, cough, and
       pleuritic chest pain. Chest radiographs showed an upper-lobe nodule in
       the first patient and a perihilar cavitary infiltrate in the second
       patient. Both patients were initially believed to have pulmonary
       tuberculosis and were treated accordingly; however, only M. xenopi grew
       on cultures of multiple respiratory specimens. This diagnosis was
       confirmed by cultures of biopsied lung tissue from the first patient and
       of fluid from a peritracheal abscess in the second patient. Both
       patients' clinical conditions improved after multidrug therapy
       (isoniazid, rifampin, pyrazinamide, ethambutol, and ciprofloxacin in the
       first case; isoniazid, rifampin, and pyrazinamide in the second case).
       The second patient's condition improved despite in vitro resistance of
       his isolate to isoniazid and rifampin.
 DE    Adult  AIDS-Related Opportunistic Infections/*DIAGNOSIS  Case Report
       Human  Male  Mycobacterium Infections, Atypical/*DIAGNOSIS
       Mycobacterium, Atypical/ISOLATION & PURIF  Tuberculosis,
       Pulmonary/*DIAGNOSIS  JOURNAL ARTICLE

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